Description

Clindamycin Sulfone is a key pharmaceutical intermediate and reference standard, currently under development. This compound is of significant interest for its role in the synthesis, analytical research, and quality control of related antibiotic substances. It serves as a critical building block for researchers and manufacturers in the pharmaceutical and fine chemical sectors. The product is available for evaluation and development purposes under CAS number 887402-22-4.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel clindamycin analogs and related antibiotic compounds.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in HPLC, LC-MS, and other analytical techniques.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for clindamycin and its derivatives.
• Impurity Profiling: Serves as a certified reference material for identifying and quantifying related substances in active pharmaceutical ingredients (APIs).
• Process Chemistry R&D: Utilized in route scouting and optimization for the development of efficient manufacturing processes.
• Academic & Institutional Research: A valuable reagent for studying structure-activity relationships (SAR) and degradation pathways in medicinal chemistry.

Basic Information

Product Name	Clindamycin Sulfone (Under Development)
CAS No.	887402-22-4
Molecular Formula	C18H33ClN2O5S
Molecular Weight	424.98 g/mol
Synonyms	Clindamycin Sulfone; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfonyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide; 7(S)-Chloro-7-deoxylincomycin Sulfone; U-34959; Lincomycin B Sulfone Derivative; Clindamycin S-Oxide; Antibiotic U-34959
EINECS	Contact for details

Quality Control

As a product under development, Clindamycin Sulfone is produced under controlled conditions with a focus on consistency and traceability. Each batch is characterized using advanced analytical techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided. Our quality system is designed to support development efforts towards GMP-grade material for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Single Unknown Impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.