Description

1-Fluoro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene, 4-Fluorophenyl 1,1,2,2-Tetrafluoroethyl Ether is a high-value fluorinated aromatic ether building block, prized for its unique combination of an electron-deficient fluorobenzene ring and a highly fluorinated ethoxy side chain. This structure is critical for imparting enhanced chemical stability, lipophilicity, and metabolic resistance in advanced material and pharmaceutical syntheses. It is primarily sought by R&D and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorine-containing components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Specialty Polymer Modifier: Incorporated into polymer backbones to create materials with superior chemical resistance, low surface energy, and improved weatherability for coatings and films.
• Organic Synthesis Reagent: Functions as a versatile fluorinated aryl ether reagent in cross-coupling reactions and nucleophilic aromatic substitution for introducing complex fluorinated groups.

Basic Information

Product Name	1-Fluoro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene, 4-Fluorophenyl 1,1,2,2-Tetrafluoroethyl Ether
CAS No.	887268-36-2
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	4-Fluorophenyl 1,1,2,2-tetrafluoroethyl ether; 1-Fluoro-4-(1,1,2,2-tetrafluoroethoxy)benzene; p-Fluorophenyl tetrafluoroethyl ether; 4-(1,1,2,2-Tetrafluoroethoxy)fluorobenzene; Benzene, 1-fluoro-4-(1,1,2,2-tetrafluoroethoxy)-; 4-Fluoro-1-(1,1,2,2-tetrafluoroethoxy)benzene; 1,1,2,2-Tetrafluoroethyl 4-fluorophenyl ether
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(1,1,2,2-Tetrafluoroethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.