Description

4'-Bromomethyl-3'-Chloro-[1,1'-Biphenyl]-2-Carbonitril is a high-purity, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and fluorescent tags for biological imaging and diagnostics.
• Cross-Coupling Reactions: The bromomethyl and chloro substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and library generation.

Basic Information

Product Name	4'-Bromomethyl-3'-Chloro-[1,1'-Biphenyl]-2-Carbonitril
CAS No.	887268-24-8
Molecular Formula	C14H9BrClN
Molecular Weight	306.58 g/mol
Synonyms	2-(4'-Bromomethyl-3'-chlorobiphenyl-2-yl)acetonitrile; 2-(4-(Bromomethyl)-3-chloro-[1,1'-biphenyl]-2-yl)acetonitrile; 3'-Chloro-4'-(bromomethyl)biphenyl-2-carbonitrile; [1,1'-Biphenyl]-2-carbonitrile, 4'-(bromomethyl)-3'-chloro-; Biphenyl-2-carbonitrile, 4'-(bromomethyl)-3'-chloro-
EINECS	Contact for details

Quality Control

Our 4'-Bromomethyl-3'-Chloro-[1,1'-Biphenyl]-2-Carbonitril is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.