Description

Ethyl 2-Fluoro-5-Nitrophenylacetate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for specialty polymers and liquid crystals where the nitro and ester functionalities allow for further chemical modifications.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce fluorinated aromatic segments into more complex structures.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of specialized fluorinated dyes and organic pigments.

Basic Information

Product Name	Ethyl 2-Fluoro-5-Nitrophenylacetate
CAS No.	887132-00-5
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	2-Fluoro-5-nitrobenzeneacetic acid ethyl ester; Ethyl (2-fluoro-5-nitrophenyl)acetate; Acetic acid, 2-(2-fluoro-5-nitrophenyl)-, ethyl ester; Ethyl 2-(2-fluoro-5-nitrophenyl)acetate; 887132-00-5; Benzeneacetic acid, 2-fluoro-5-nitro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Fluoro-5-Nitrophenylacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.