Description

2,6-Difluoro-4-Iodoanisole is a high-value, multi-functional halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture, featuring iodine and fluorine substituents on an anisole core, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and as a precursor to novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic systems for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro and iodo groups contribute to binding affinity and environmental stability.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as ligands for OLEDs or charge-transport materials, due to its ability to modify HOMO/LUMO energy levels.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, leveraging the reactive iodine atom for carbon-carbon bond formation.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystal compounds, imparting specific dielectric and thermal properties.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	2,6-Difluoro-4-Iodoanisole
CAS No.	886762-68-1
Molecular Formula	C7H5F2IO
Molecular Weight	269.02 g/mol
Synonyms	4-Iodo-2,6-difluoroanisole; 1-Iodo-2,6-difluoro-4-methoxybenzene; 2,6-Difluoro-1-iodo-4-methoxybenzene; Anisole, 2,6-difluoro-4-iodo-; 886762-68-1; 4-Methoxy-2,6-difluoro-1-iodobenzene
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Iodoanisole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.