Description

2-Bromo-5-Fluorophenylacetonitrile is a versatile and high-purity fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its bromo and fluoro substituents enable precise structural modifications. It is primarily sought after by research chemists and process development scientists for creating active pharmaceutical ingredients (APIs), advanced agrochemicals, and functional materials. Our supply ensures consistent quality and reliable availability for your most demanding synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers and organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	2-Bromo-5-Fluorophenylacetonitrile
CAS No.	886761-96-2
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	(2-Bromo-5-fluorophenyl)acetonitrile; 2-Bromo-5-fluorobenzyl cyanide; α-Bromo-5-fluorophenylacetonitrile; 886761-96-2; 5-Fluoro-2-bromophenylacetonitrile; 2-Bromo-5-fluoro-benzeneacetonitrile; (2-Bromo-5-fluorophenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluorophenylacetonitrile is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency suitable for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.