Description

3-Fluoro-4-(trifluoromethoxy)phenylacetic acid is a high-value fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring modified pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs contribute to efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Acts as a building block for electron-deficient aromatic units in the development of organic semiconductors and OLED materials.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring structure-activity relationships (SAR) in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A key starting material for specialty chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	886761-70-2
Molecular Formula	C9H6F4O3
Molecular Weight	238.14 g/mol
Synonyms	2-[3-Fluoro-4-(trifluoromethoxy)phenyl]acetic acid; 3-Fluoro-4-(trifluoromethoxy)benzeneacetic acid; α-(3-Fluoro-4-(trifluoromethoxy)phenyl)acetic acid; 4-(Trifluoromethoxy)-3-fluorophenylacetic acid; 886761-70-2; 3-Fluoro-4-trifluoromethoxyphenylacetic acid; (3-Fluoro-4-(trifluoromethoxy)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(trifluoromethoxy)phenylacetic acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.