Description

3,5-Difluoro-2-Methoxyphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluoro-methoxy motif can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research: A valuable reagent for academic and industrial research in medicinal chemistry and fluorination methodology.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	3,5-Difluoro-2-Methoxyphenylacetic Acid
CAS No.	886761-63-3
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2-(3,5-Difluoro-2-methoxyphenyl)acetic Acid; (3,5-Difluoro-2-methoxyphenyl)acetic Acid; 3,5-Difluoro-2-methoxybenzeneacetic Acid; α-(3,5-Difluoro-2-methoxyphenyl)acetic Acid; NSC 886761; 886761-63-3; Difluoromethoxyphenylacetic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methoxyphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.