Description

2,3-Difluoro-4-Methoxyphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and methoxy group, enabling precise molecular modifications. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting selective enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro-methoxy phenylacetic acid structure can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering properties like solubility, thermal stability, and surface energy for specialty coatings and high-performance materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination reactions and constructing complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2,3-Difluoro-4-Methoxyphenylacetic Acid
CAS No.	886503-70-4
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2-(2,3-Difluoro-4-methoxyphenyl)acetic Acid; 2,3-Difluoro-4-methoxybenzeneacetic Acid; α-(2,3-Difluoro-4-methoxyphenyl)acetic Acid; (2,3-Difluoro-4-methoxyphenyl)ethanoic Acid; 886503-70-4; DFMPAA; Difluoromethoxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxyphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.