Description

2,6-Difluoro-3-Methylbenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine atoms and a reactive nitrile group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly for molecules requiring a difluoromethylbenzene core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials used in displays and lighting.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyano group transformations to create complex aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	2,6-Difluoro-3-Methylbenzonitrile
CAS No.	886502-09-6
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	3-Methyl-2,6-difluorobenzonitrile; 2,6-Difluoro-3-methylbenzonitrile; 2,6-Difluoro-m-tolunitrile; Benzonitrile, 2,6-difluoro-3-methyl-; 886502-09-6
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 2,6-Difluoro-3-Methylbenzonitrile typically meets a purity specification of ≥97% (by HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications, including higher purity grades (≥98%, ≥99%), to meet specific project requirements in pharmaceutical or electronic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.