Description

4-Fluoro-3,5-Dimethylbenzamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and liquid crystals.
• Chemical Biology Probes: Useful for creating fluorinated probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	4-Fluoro-3,5-Dimethylbenzamide
CAS No.	886501-71-9
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	3,5-Dimethyl-4-fluorobenzamide; 4-Fluoro-3,5-dimethylbenzamide; Benzamide, 4-fluoro-3,5-dimethyl-; 886501-71-9; AI3-32466; AKOS025310947; BRN 2872695; CS-W012767; FT-0773295; SCHEMBL2182707
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3,5-Dimethylbenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.