Description

4-Fluoro-3-(Trifluoromethoxy)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethoxy and acetic acid functional groups, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4-Fluoro-3-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	886501-32-2
Molecular Formula	C9H6F4O3
Molecular Weight	238.14 g/mol
Synonyms	2-[4-Fluoro-3-(trifluoromethoxy)phenyl]acetic Acid; 4-Fluoro-3-(trifluoromethoxy)benzeneacetic Acid; 4-Fluoro-α-(trifluoromethoxy)phenylacetic Acid; (4-Fluoro-3-trifluoromethoxyphenyl)acetic Acid; 886501-32-2; F3MOPAA; 4-F-3-TFM-PAA
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Trifluoromethoxy)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.