Description

3-Chloro-2,4-Difluorobenzamide is a high-purity fluorinated benzamide derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular structure, which enables the introduction of chloro and difluoro substituents into complex target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluorobenzamide core contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers and liquid crystals, leveraging its halogenated aromatic structure.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in HPLC and GC-MS analysis.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct more complex, functionalized aromatic systems.

Basic Information

Product Name	3-Chloro-2,4-Difluorobenzamide
CAS No.	886501-21-9
Molecular Formula	C7H4ClF2NO
Molecular Weight	191.56 g/mol
Synonyms	3-Chloro-2,4-difluorobenzoic acid amide; 2,4-Difluoro-3-chlorobenzamide; Benzamide, 3-chloro-2,4-difluoro-; 886501-21-9; Amides, C7-18; 3-Chloro-2,4-difluoro-benzoic acid amide
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4-Difluorobenzamide is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.