Description

4-Chloro-3-(Trifluoromethoxy)Benzamide is a high-purity, synthetically versatile benzamide derivative distinguished by its chloro and trifluoromethoxy substituents. This compound is a critical pharmaceutical intermediate and agrochemical building block, valued for its role in synthesizing advanced active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with enhanced biological activity and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial precursor for developing next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Used in organic and medicinal chemistry research to create specialized ligands for catalysis or as a scaffold for probing biological targets.
• Material Science Research: Investigated as a monomer or additive for synthesizing advanced polymers with specific thermal or chemical resistance properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific benzamide backbone.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Benzamide
CAS No.	886500-81-8
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	4-Chloro-3-(trifluoromethoxy)benzamide; Benzamide, 4-chloro-3-(trifluoromethoxy)-; 886500-81-8; 4-Chloro-α,α,α-trifluoro-3-methoxy-benzamide; 3-Trifluoromethoxy-4-chlorobenzamide; 4-Chloro-3-trifluoromethoxybenzamide; 4-Chloro-3-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethoxy)Benzamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.