Description

2-Bromo-4-Chloro-6-Fluoroanisole is a high-purity, multi-halogenated anisole derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the life sciences sector who require precise building blocks for developing new active ingredients, such as drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogen pattern contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystals with unique electronic or optical properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.

Basic Information

Product Name	2-Bromo-4-Chloro-6-Fluoroanisole
CAS No.	886499-78-1
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-2-methoxybenzene; 2-Methoxy-5-bromo-3-chloro-1-fluorobenzene; Anisole, 2-bromo-4-chloro-6-fluoro-; 886499-78-1; 2-Bromo-4-chloro-6-fluoromethoxybenzene; 5-Bromo-3-chloro-1-fluoro-2-methoxybenzene; Benzene, 1-bromo-3-chloro-5-fluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-6-Fluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.