Description

3-(2,3,5-Trifluorophenyl)Propanoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethylphenyl moiety imparts desirable metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine atoms for enhanced bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved stability and performance.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for next-generation display and lighting technologies.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into polymers, enhancing their chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	3-(2,3,5-Trifluorophenyl)Propanoic Acid
CAS No.	886499-45-2
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-(2,3,5-Trifluorophenyl)propionic Acid; 2,3,5-Trifluorohydrocinnamic Acid; β-(2,3,5-Trifluorophenyl)propanoic Acid; (2,3,5-Trifluorophenyl)propanoic Acid; 886499-45-2; 3-(2,3,5-Trifluorophenyl)propanoate; NSC 886499
EINECS	Contact for details

Quality Control

Every batch of 3-(2,3,5-Trifluorophenyl)Propanoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.