Description

2,6-Difluoro-4-Methoxyphenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing fluorine atoms and an electron-donating methoxy group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for high-performance displays and optical devices.
• Organic Electronics: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Advanced Material Research: Acts as a building block for polymers and specialty chemicals requiring specific dielectric or surface properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Item	Details
Product Name	2,6-Difluoro-4-Methoxyphenylacetonitrile
CAS No.	886499-03-2
Molecular Formula	C9H7F2NO
Molecular Weight	183.15 g/mol
Synonyms	2,6-Difluoro-4-methoxybenzyl cyanide; (2,6-Difluoro-4-methoxyphenyl)acetonitrile; 4-Methoxy-2,6-difluorobenzyl cyanide; α-Cyano-2,6-difluoro-4-methoxytoluene; 886499-03-2; 2,6-Difluoro-4-methoxybenzeneacetonitrile; 2,6-Difluoro-p-methoxyphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.