Description

3,5-Difluoro-4-Methoxyphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the difluoro-methoxy substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in high-performance display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile building block for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.
• Peptide Mimetics & Bio-conjugation: The acetic acid moiety allows for coupling reactions to create fluorinated peptide analogs or labeling agents.

Basic Information

Product Name	3,5-Difluoro-4-Methoxyphenylacetic Acid
CAS No.	886498-74-4
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2-(3,5-Difluoro-4-methoxyphenyl)acetic Acid; (3,5-Difluoro-4-methoxyphenyl)acetic Acid; 4-Methoxy-3,5-difluorophenylacetic Acid; 3,5-Difluoro-4-methoxybenzeneacetic Acid; α-(3,5-Difluoro-4-methoxyphenyl)acetic Acid; DFMPAA; 886498-74-4 (CAS Name)
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methoxyphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for sensitive applications like pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.