Description

2,3-Dichloro-6-Fluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile molecular structure, which serves as a critical precursor for the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated phenylacetic acid motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Active Ingredient Development: Used in the research and production of advanced herbicides and fungicides, where the fluorine and chlorine substitutions enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Organic Ligand & Catalyst Preparation: Utilized to create specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new chemical entities in medicinal and material chemistry.

Basic Information

Product Name	2,3-Dichloro-6-Fluorophenylacetic Acid
CAS No.	886497-57-0
Molecular Formula	C8H5Cl2FO2
Molecular Weight	223.03 g/mol
Synonyms	(2,3-Dichloro-6-fluorophenyl)acetic acid; 2-(2,3-Dichloro-6-fluorophenyl)acetic acid; 2,3-Dichloro-6-fluoro-benzeneacetic acid; α-(2,3-Dichloro-6-fluorophenyl)acetic acid; NSC 886497; 886497-57-0; 2,3-Dichloro-6-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-6-Fluorophenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.