Description

2-(3-Chloro-5-(Trifluoromethyl)Phenyl)Acetonitrile is a high-value, multi-functional aromatic nitrile building block essential for advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and functional molecules for advanced polymers, liquid crystals, and electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(3-Chloro-5-(Trifluoromethyl)Phenyl)Acetonitrile
CAS No.	886496-95-3
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	[3-Chloro-5-(trifluoromethyl)phenyl]acetonitrile; 2-(3-Chloro-5-(trifluoromethyl)phenyl)ethanenitrile; (3-Chloro-5-trifluoromethylphenyl)acetonitrile; 3-Chloro-α-trifluoromethylphenylacetonitrile; α-Cyano-3-chloro-5-trifluoromethyltoluene; 886496-95-3; 2-(3-Chloro-5-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-5-(Trifluoromethyl)Phenyl)Acetonitrile is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.