Description

4-Chloro-2-(Trifluoromethyl)Benzamide is a high-purity, specialized organic intermediate featuring a benzamide core substituted with chloro and trifluoromethyl groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical actives and agrochemicals, where the trifluoromethyl moiety is prized for enhancing metabolic stability and lipophilicity. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where specific halogen and fluorine substitutions are required for desired electronic or physical properties.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)Benzamide
CAS No.	886496-79-3
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)benzamide; 2-Trifluoromethyl-4-chlorobenzamide; 4-Chloro-alpha,alpha,α-trifluoro-o-toluamide; Benzamide, 4-chloro-2-(trifluoromethyl)-; 886496-79-3; 4-Chloro-2-trifluoromethylbenzamide
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethyl)Benzamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.