Description

2'-Methyl-2,2,2,3'-Tetrafluoroacetophenone is a specialized fluorinated aromatic ketone building block, valued for its unique electronic and steric properties imparted by the trifluoromethyl and tetrafluoro-substituted aromatic ring. This compound is critical for introducing fluorinated motifs into target molecules, which can dramatically alter their lipophilicity, metabolic stability, and binding affinity. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic additions, and as a precursor for heterocyclic compounds in academic and industrial R&D.
• Polymer Modification: Used to incorporate fluorine into polymer chains, potentially improving chemical resistance, thermal stability, and surface properties of specialty polymers.

Basic Information

Product Name	2'-Methyl-2,2,2,3'-Tetrafluoroacetophenone
CAS No.	886370-05-4
Molecular Formula	C9H6F4O
Molecular Weight	206.14 g/mol
Synonyms	1-(2-Methyl-3,4,5,6-tetrafluorophenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-methyl-3,4,5,6-tetrafluorophenyl)ethanone; 2'-Methyl-α,α,α,3'-tetrafluoroacetophenone; 2-Methyl-3,4,5,6-tetrafluoro-α,α,α-trifluoroacetophenone; α,α,α,3'-Tetrafluoro-2'-methylacetophenone
EINECS	Contact for details

Quality Control

Our 2'-Methyl-2,2,2,3'-Tetrafluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.