Description

6-Benzyloxy-1H-Indazole-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its indazole core functionalized with benzyloxy and nitrile groups. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and CNS drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs and investigational new chemical entities (NCEs).
• Kinase Inhibitor Development: Serves as a core scaffold for constructing potent and selective kinase inhibitors, a major class of oncology therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to improve drug potency and pharmacokinetic properties.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	6-Benzyloxy-1H-Indazole-3-Carbonitrile
CAS No.	886369-60-4
Molecular Formula	C15H11N3O
Molecular Weight	249.27 g/mol
Synonyms	6-Benzyloxy-1H-indazole-3-carbonitrile; 6-(Benzyloxy)-1H-indazole-3-carbonitrile; 1H-Indazole-3-carbonitrile, 6-(phenylmethoxy)-; 6-O-Benzyl-1H-indazole-3-carbonitrile; 3-Cyano-6-benzyloxyindazole; 6-Benzyloxyindazole-3-carbonitrile; BNBC
EINECS	Contact for details

Quality Control

Our 6-Benzyloxy-1H-Indazole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.