Description

C-[1-(2-Fluoro-Phenyl)-Cyclopropyl]-Methylamine is a high-purity, fluorinated cyclopropylamine building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which combines a strained cyclopropane ring with a fluorinated aromatic system, enabling precise modulation of molecular properties in target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and cyclopropyl group enhance bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or polymers with tailored electronic properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways due to its fluorine label.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and custom synthesis projects requiring reliable, high-quality advanced intermediates.

Basic Information

Product Name	C-[1-(2-Fluoro-Phenyl)-Cyclopropyl]-Methylamine
CAS No.	886365-63-5
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-(2-Fluorophenyl)cyclopropanemethanamine; (1-(2-Fluorophenyl)cyclopropyl)methanamine; α-Methyl-1-(2-fluorophenyl)cyclopropanemethylamine; 2-Fluoro-α-(aminomethyl)benzenecarbocyclopropane; (1-(o-Fluorophenyl)cyclopropyl)methylamine; C-(1-(2-Fluorophenyl)cyclopropyl)methylamine; 886365-63-5 (CAS Name)
EINECS	Contact for details

Quality Control

Every batch of C-[1-(2-Fluoro-Phenyl)-Cyclopropyl]-Methylamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up applications. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC or GC), chiral purity (if applicable), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC / GC)	≥ 97.0%
Purity (Chiral HPLC)	Contact for details (enantiomerically pure or racemic)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.