Description

4-Fluoro-2-Methylindole-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both fluorine and an ethyl ester group, makes it a versatile building block for constructing complex heterocyclic compounds with tailored properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Chemical Biology: Utilized as a probe or tag in the design of molecules for studying biological processes and enzyme inhibition.

Basic Information

Product Name	4-Fluoro-2-Methylindole-3-Carboxylic Acid Ethyl Ester
CAS No.	886362-68-1
Molecular Formula	C₁₂H₁₂FNO₂
Molecular Weight	221.23 g/mol
Synonyms	Ethyl 4-Fluoro-2-methyl-1H-indole-3-carboxylate; 4-Fluoro-2-methylindole-3-carboxylic acid ethyl ester; 1H-Indole-3-carboxylic acid, 4-fluoro-2-methyl-, ethyl ester; 2-Methyl-4-fluoroindole-3-carboxylic acid ethyl ester; 4-Fluoro-2-methyl-1H-indole-3-carboxylic acid ethyl ester; Ethyl 4-fluoro-2-methylindole-3-carboxylate; 886362-68-1
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-2-Methylindole-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.