Description

2,3,4,5,6-Pentafluorophenyl 1-Naphthalenesulphonate CAS NO 886361-18-8 is a specialized fluorinated sulfonate ester compound, serving as a high-value synthetic intermediate and derivatization agent. Its core value lies in its unique molecular architecture, which combines a highly electron-deficient pentafluorophenyl group with a bulky naphthalene sulfonate moiety, making it a powerful reagent for introducing the sulfonate leaving group in nucleophilic substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for synthesizing active pharmaceutical ingredients (APIs), creating functional polymers, and developing novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug molecules, especially in creating sulfonate ester prodrugs or modifying bioactive compounds.
• Polymer Chemistry: Used as a functional monomer or cross-linking agent in the production of specialty polymers with enhanced thermal stability and chemical resistance.
• Agrochemical Synthesis: Employed in the development of next-generation herbicides and pesticides, where the fluorinated aromatic system contributes to biological activity and environmental stability.
• Material Science: Acts as a surface modification agent or a precursor for creating advanced coatings and electronic materials.
• Chemical Derivatization: Utilized in analytical chemistry as a derivatization reagent for chromatography or mass spectrometry to improve detection of specific analytes.
• Research & Development: Serves as a versatile tool in organic synthesis laboratories for exploring new reaction pathways and creating novel chemical entities.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 1-Naphthalenesulphonate
CAS No.	886361-18-8
Molecular Formula	C₁₆H₇F₅O₃S
Molecular Weight	374.28 g/mol
Synonyms	1-Naphthalenesulfonic acid, 2,3,4,5,6-pentafluorophenyl ester; Pentafluorophenyl 1-naphthalenesulfonate; 1-Naphthalenesulfonyl pentafluorophenyl ester; PFN-Sulfonate; NSC 886361; Pentafluorophenyl naphthalene-1-sulfonate
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 1-Naphthalenesulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.