Description

2-(Trifluoromethoxy)Ethylamine, Hydrochloride is a high-purity, specialty organic salt featuring a trifluoromethoxy functional group. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce fluorine-containing motifs that can dramatically alter the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and other advanced materials to modify surface properties and thermal stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2-(Trifluoromethoxy)Ethylamine, Hydrochloride
CAS No.	886050-51-7
Molecular Formula	C₃H₇ClF₃NO
Molecular Weight	177.54 g/mol
Synonyms	2-(Trifluoromethoxy)ethanamine hydrochloride; 1-Amino-2-(trifluoromethoxy)ethane hydrochloride; 2-Aminoethyl trifluoromethyl ether hydrochloride; Ethylamine, 2-(trifluoromethoxy)-, hydrochloride; TFMOEA·HCl
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Ethylamine, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.