Description

2-(2,6-Difluoro-Phenyl)-Acetamidine is a high-purity, fine chemical intermediate characterized by its amidine functional group flanked by a difluorinated phenyl ring. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific fluorine substitution pattern is leveraged to modulate biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atoms enhance lipophilicity and target binding.
• Chemical Research & Development: Serves as a versatile building block for organic chemists exploring new heterocyclic compounds and functional materials.
• Ligand and Catalyst Preparation: The amidine group can act as a coordinating ligand or be used to prepare catalysts for organic transformations.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(2,6-Difluoro-Phenyl)-Acetamidine
CAS No.	885965-71-9
Molecular Formula	C8H8F2N2
Molecular Weight	170.16 g/mol
Synonyms	2-(2,6-Difluorophenyl)acetamidine; 2,6-Difluorophenylacetamidine; Acetamidine, 2-(2,6-difluorophenyl)-; 2-(2,6-Difluoro-phenyl)-acetamidine; 885965-71-9; 2-(2,6-Difluorophenyl)ethanimidamide
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluoro-Phenyl)-Acetamidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.