Description

2-Fluoro-3-Trifluoromethyl-Benzamidine is a high-purity, fluorinated benzamidine derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a reactive amidine group with fluorine and trifluoromethyl substituents, enabling precise modifications to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging the bioactivity of the fluorinated benzamidine core.
• Material Science: Serves as a building block for specialty polymers and advanced materials requiring specific fluorine-based properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 2-fluoro-3-trifluoromethyl-phenyl moiety into complex organic molecules.
• Life Science Research: Employed in biochemical studies and as a scaffold for designing molecular probes and enzyme inhibitors.

Basic Information

Product Name	2-Fluoro-3-Trifluoromethyl-Benzamidine
CAS No.	885957-14-2
Molecular Formula	C8H6F4N2
Molecular Weight	206.14 g/mol
Synonyms	2-Fluoro-3-(trifluoromethyl)benzamidine; 2-Fluoro-alpha,alpha,α-trifluoro-m-toluamidine; 2-Fluoro-3-trifluoromethylbenzenecarboximidamide; 885957-14-2; m-Toluamidine, 2-fluoro-alpha,alpha,α-trifluoro-; Benzamidine, 2-fluoro-3-(trifluoromethyl)-; 3-Trifluoromethyl-2-fluorobenzamidine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Trifluoromethyl-Benzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.