Description

2-Iodo-Benzamidine is a high-purity, halogenated benzamidine derivative with significant utility as a specialized chemical intermediate. Its unique structure, featuring both an amidine group and an iodine substituent, makes it a valuable building block for synthesizing more complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists working in medicinal chemistry, where it serves as a key precursor for the development of novel enzyme inhibitors and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly protease inhibitors and other enzyme-targeting therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive molecules.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and protein functions.
• Organic Synthesis: Acts as a versatile intermediate for introducing the benzamidine moiety into more complex organic frameworks via cross-coupling and other reactions.
• Bioconjugation & Labeling: The iodine atom provides a handle for further functionalization, useful in labeling and conjugation strategies.

Basic Information

Item	Details
Product Name	2-Iodo-Benzamidine
CAS No.	885953-16-2
Molecular Formula	C7H7IN2
Molecular Weight	246.05 g/mol
Synonyms	2-Iodobenzamidine; o-Iodobenzamidine; Benzenecarboximidamide, 2-iodo-; 2-Iodobenzenecarboximidamide; (2-Iodophenyl)methanimidamide; 885953-16-2; CAS 885953-16-2
EINECS	Contact for details

Quality Control

Our 2-Iodo-Benzamidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data with each shipment, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available upon request and are prepared in accordance with current industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.