Description

2,3,4,5,6-Pentafluorophenyl 2-Naphthalenesulphonate CAS NO 885950-37-8 is a specialized fluorinated sulfonate ester compound, serving as a high-value intermediate in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a perfluorinated phenyl group with a naphthalene sulfonate moiety, making it a versatile reagent for introducing fluorinated aromatic systems. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic rings for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved lipophilicity and biological activity.
• Material Science Research: Acts as a precursor or modifying agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Serves as an electrophilic partner in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Fluorination Reagent: Utilized as a source of the pentafluorophenyl group in nucleophilic aromatic substitution reactions.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent probes or affinity labels for studying biological systems.

Basic Information

Item	Detail
Product Name	2,3,4,5,6-Pentafluorophenyl 2-Naphthalenesulphonate
CAS No.	885950-37-8
Molecular Formula	C₁₆H₇F₅O₃S
Molecular Weight	374.28 g/mol
Synonyms	2-Naphthalenesulfonic Acid 2,3,4,5,6-Pentafluorophenyl Ester; Pentafluorophenyl 2-Naphthalenesulfonate; 2-Naphthylsulfonyl Pentafluorobenzene; 2,3,4,5,6-Pentafluorophenyl Naphthalene-2-sulfonate; PFBNS; 2-(Pentafluorophenylsulfonyl)naphthalene (related structure); Naphthalene-2-sulfonic Acid Pentafluorophenyl Ester
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 2-Naphthalenesulphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.