Description

(4-Aminophenyl)(4-[4-(Trifluoromethyl)Phenyl]Piperazino)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperazine and trifluoromethylphenyl functional groups. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system. Pharmaceutical R&D departments and fine chemical manufacturers need this building block to develop new drug candidates with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and psychiatric disorders.
• Biochemical Research: Used in academic and industrial research for studying receptor-ligand interactions and structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and development of new crop protection agents and pesticides.
• Material Science: Investigated for the creation of specialty polymers and advanced organic materials with specific electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	(4-Aminophenyl)(4-[4-(Trifluoromethyl)Phenyl]Piperazino)Methanone
CAS No.	885949-76-8
Molecular Formula	C18H18F3N3O
Molecular Weight	349.35 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-4-[(4-aminobenzoyl)]piperazine; 4-Amino-N-[4-(4-(trifluoromethyl)phenyl)piperazin-1-yl]benzamide; 4'-Amino-4-[4-(trifluoromethyl)phenyl]piperazine-1-carboxanilide; (4-Aminobenzoyl)-4-(4-trifluoromethylphenyl)piperazine; 885949-76-8; 4-[4-(4-Aminobenzoyl)piperazin-1-yl]benzotrifluoride
EINECS	Contact for details

Quality Control

Our (4-Aminophenyl)(4-[4-(Trifluoromethyl)Phenyl]Piperazino)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.