Description

4-Fluoro-3-(1H)Indazole Carboxylic Acid is a high-purity, heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and oncology drug discovery programs. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors targeting various cancers and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Chemical Biology Probes: Serves as a core scaffold for developing selective enzyme inhibitors and biological probes.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule libraries and API route scouting.
• Agrochemical Research: Potential intermediate in the discovery of new herbicides and fungicides with novel modes of action.
• Material Science: Exploration as a monomer or functional component in advanced polymers and specialty materials.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-(1H)Indazole Carboxylic Acid
CAS No.	885521-64-2
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	4-Fluoro-1H-indazole-3-carboxylic acid; 4-Fluoro-3-carboxyindazole; 4-Fluoroindazole-3-carboxylic acid; 885521-64-2; 4-Fluoro-3-(1H-indazole)carboxylic acid; 3-Carboxy-4-fluoro-1H-indazole; 1H-Indazole-3-carboxylic acid, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(1H)Indazole Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.