Description

Fluoroiodoacetonitrile 97 CAS NO 885276-30-2 is a high-purity, highly volatile organoiodine building block characterized by its reactive cyano and halogen functionalities. This compound is critical for introducing fluorine and iodine atoms into complex molecular architectures, enabling advanced synthetic pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions, fluorination processes, and as a precursor for specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine-iodine motif enhances biological activity.
• Material Science Precursor: Employed in the synthesis of specialized polymers, liquid crystals, and organic electronic materials requiring halogenated nitrile components.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed reactions (e.g., Sonogashira, Negishi) for carbon-carbon bond formation.
• Fluorination Reagent: Utilized as a source of fluorine in nucleophilic and radical fluorination strategies to create C-F bonds.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules and probes for studying biological mechanisms and diagnostics.

Basic Information

Product Name	Fluoroiodoacetonitrile 97
CAS No.	885276-30-2
Molecular Formula	C2HFIN
Molecular Weight	194.93 g/mol
Synonyms	2-Fluoro-2-iodoacetonitrile; Iodofluoroacetonitrile; Fluoro(iodo)acetonitrile; Acetonitrile, fluoroiodo-; 2-Fluoro-2-iodoethanenitrile; (Fluoroiodo)acetonitrile; NCCHFI; 885276-30-2
EINECS	Contact for details

Quality Control

Our Fluoroiodoacetonitrile 97 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure a typical purity of ≥97% and conformity to specified impurity profiles. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, the container should be kept tightly sealed when not in use and handled under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.