Description

6,8-Dibromo-2H-chromene-3-carbonitrile is a halogenated chromene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable chemical building block for constructing complex heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with potential for improved efficacy and selectivity.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme mechanisms or as a fluorescent tag precursor due to its chromene core.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and cyclization reactions to create diverse chemical libraries.

Basic Information

Product Name	6,8-Dibromo-2H-chromene-3-carbonitrile
CAS No.	885271-32-9
Molecular Formula	C10H5Br2NO
Molecular Weight	330.96 g/mol
Synonyms	6,8-Dibromo-2H-1-benzopyran-3-carbonitrile; 6,8-Dibromo-3-cyano-2H-chromene; 2H-1-Benzopyran-3-carbonitrile, 6,8-dibromo-; 3-Cyano-6,8-dibromo-2H-chromene; 6,8-Dibromo-2H-chromene-3-carbonitrile; 885271-32-9 (CAS); 6,8-Dibromo-3-cyanocoumarin (related structure)
EINECS	Contact for details

Quality Control

Our 6,8-Dibromo-2H-chromene-3-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.