Description

(2-Amino-6-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle, protected by the acid-labile tert-butoxycarbonyl (Boc) group, for the controlled construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its aromatic amine core is incorporated into active molecules.
• Peptide Mimetics & Conjugates: Serves as a protected aniline precursor for creating non-natural amino acids and peptide-like structures in bioconjugation and drug delivery systems.
• Material Science Research: Employed as a monomer or functionalization agent in the development of specialty polymers, dyes, and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	(2-Amino-6-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	885270-79-1
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	2-Methyl-6-[(tert-butoxycarbonyl)amino]aniline; N-Boc-2,6-diaminotoluene; tert-Butyl (2-amino-6-methylphenyl)carbamate; 2-Amino-6-methylaniline N-Boc derivative; Boc-2,6-diaminotoluene; N-(tert-Butoxycarbonyl)-2,6-diaminotoluene; 6-Methyl-1,2-phenylenediamine, N1-Boc protected; (2-Amino-6-methylphenyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (2-Amino-6-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for GMP-grade intermediates and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.