Description

2-Chloro-N-(2,4,5-trifluorophenyl)acetamide is a specialized fluorinated acetamide derivative, a key synthetic intermediate in modern organic chemistry. Its value lies in its precise molecular structure, which incorporates both chloro and trifluorophenyl moieties, making it an essential building block for constructing complex, high-value molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-infective properties.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated aromatic system.
• Material Science Research: Used in the development of novel organic materials, including liquid crystals and polymers, where fluorine substitution can modify physical properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in probe development and biochemical assay tools.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	2-Chloro-N-(2,4,5-trifluorophenyl)acetamide
CAS No.	885267-45-8
Molecular Formula	C8H4ClF3NO
Molecular Weight	219.57 g/mol
Synonyms	2-Chloro-N-(2,4,5-trifluorophenyl)acetamide; Acetamide, 2-chloro-N-(2,4,5-trifluorophenyl)-; N-(2,4,5-Trifluorophenyl)-2-chloroacetamide; 2-Chloro-2',4',5'-trifluoroacetanilide; α-Chloro-2,4,5-trifluoroacetanilide; 885267-45-8; CAS 885267-45-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(2,4,5-trifluorophenyl)acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.