Description

Acetamide, n-(3-Chloro-5-Hydroxyphenyl)- is a specialized aromatic amide derivative of significant interest in advanced organic synthesis. This compound matters as a key building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique chlorophenol-acetamide scaffold. Pharmaceutical and agrochemical research and development (R&D) departments, as well as fine chemical manufacturers, need this high-purity intermediate to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in research for creating specialized ligands in coordination chemistry and catalytic systems.
• Material Science Research: Investigated as a monomer or additive for synthesizing specialized polymers with unique thermal or optical properties.
• Biochemical Research: Employed in proteomics and enzyme inhibition studies due to its amide functionality and phenolic group.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex organic dyes and pigments.

Basic Information

Product Name	Acetamide, n-(3-Chloro-5-Hydroxyphenyl)-
CAS No.	885044-43-9
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	N-(3-Chloro-5-hydroxyphenyl)acetamide; 3'-Chloro-5'-hydroxyacetanilide; 1-(3-Chloro-5-hydroxyphenyl)ethanone; 3-Chloro-5-acetamidophenol; 5-Acetamido-3-chlorophenol; Acetamide, N-(3-chloro-5-hydroxyphenyl)-; N-Acetyl-3-chloro-5-aminophenol
EINECS	Contact for details

Quality Control

Our Acetamide, n-(3-Chloro-5-Hydroxyphenyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques like HPLC, GC, and NMR. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.