Description

4-(3-Bromophenyl)-4-Oxobutyronitrile is a versatile brominated aromatic nitrile ketone intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the construction of complex pharmacologically active molecules and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing brominated aryl and nitrile functionalities.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the reactivity of the bromine and nitrile groups.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions.
• Material Science: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where specific bromo-aromatic units are required.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes and tags used in biochemical and cellular studies.
• Custom Synthesis: Provides a versatile handle for contract research organizations (CROs) and custom synthesis houses to fulfill client-specific molecular assembly requests.

Basic Information

Product Name	4-(3-Bromophenyl)-4-Oxobutyronitrile
CAS No.	884504-63-6
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	4-(3-Bromobenzoyl)butyronitrile; 4-Oxo-4-(3-bromophenyl)butanenitrile; 3-Bromobenzoylacetonitrile; γ-Oxo-3-bromobenzene butyronitrile; 4-(3-Bromophenyl)-4-oxobutanenitrile; 3'-Bromobenzoylacetonitrile; 1-(3-Bromophenyl)-4-cyanobutan-1-one
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenyl)-4-Oxobutyronitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.