Description

5-(2-Bromophenyl)-5-Oxovaleronitrile is a specialized brominated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both an electrophilic carbonyl and a versatile nitrile group adjacent to a brominated phenyl ring, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the bromophenyl moiety can contribute to biological activity.
• Ligand and Catalyst Precursor: Acts as a starting material for the preparation of specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Heterocyclic Chemistry: Employed in cyclization reactions, such as the formation of pyrroles, pyridines, and other nitrogen-containing heterocycles, which are core structures in many bioactive molecules.
• Material Science: Investigated as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.

Basic Information

Product Name	5-(2-Bromophenyl)-5-Oxovaleronitrile
CAS No.	884504-59-0
Molecular Formula	C11H10BrNO
Molecular Weight	252.11 g/mol
Synonyms	5-(2-Bromobenzoyl)valeronitrile; 4-Cyano-1-(2-bromophenyl)-1-butanone; 2-Bromophenyl 4-cyanobutyl ketone; 5-Oxo-5-(2-bromophenyl)pentanenitrile; 1-(2-Bromophenyl)-4-cyanobutan-1-one; γ-Cyano-2'-bromopropiophenone; 5-(2-Bromophenyl)-5-oxopentanenitrile
EINECS	Contact for details

Quality Control

Our 5-(2-Bromophenyl)-5-Oxovaleronitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.