Description

3',5'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone is a high-purity fluorinated organic intermediate featuring a propiophenone core protected by a 1,3-dioxane acetal group. This compound is valued for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly those requiring selective fluorination. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the difluoro and acetal functionalities impart specific biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with unique optical or surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions at the ketone or acetal groups.
• Fluorine Chemistry Studies: Utilized as a model compound in methodological development for introducing and manipulating fluorine atoms in organic molecules.

Basic Information

Product Name	3',5'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone
CAS No.	884504-29-4
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	2-(3,5-Difluorobenzoyl)ethylidene 1,3-dioxane; 1-(3,5-Difluorophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3,5-Difluoro-3-(1,3-dioxan-2-yl)propiophenone; 3',5'-Difluoro-3-(1,3-dioxan-2-yl)-1-propanone; Propiophenone, 3',5'-difluoro-3-(1,3-dioxan-2-yl)-; 884504-29-4; 3-(1,3-Dioxan-2-yl)-1-(3,5-difluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.