Description

3',4'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone is a high-value fluorinated organic intermediate featuring a propiophenone core protected by a 1,3-dioxane acetal group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and advanced materials sectors. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers where the introduction of fluorine atoms and protected carbonyl functionality is strategically important.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluoro moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed in the synthesis of specialty fluoropolymers with unique thermal, chemical, and surface properties.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies in fluorine chemistry and protective group strategies.
• Custom Synthesis & Contract Manufacturing: A requested compound for bespoke synthesis projects requiring specific fluorinated aromatic ketone structures.

Basic Information

Product Name	3',4'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone
CAS No.	884504-28-3
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3,4-Difluoro-3-(1,3-dioxan-2-yl)propiophenone; 2-[3-(3,4-Difluorophenyl)-3-oxopropyl]-1,3-dioxane; Propiophenone, 3',4'-difluoro-3-(1,3-dioxan-2-yl)-; 884504-28-3; 3-(1,3-Dioxan-2-yl)-1-(3,4-difluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and advanced material applications. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.