Description

2',5'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone is a high-purity fluorinated organic intermediate featuring a protected carbonyl group. This compound is critical for its role as a key building block in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API (Active Pharmaceutical Ingredient) Synthesis: Used in the construction of complex molecular scaffolds for potential therapeutics targeting neurological and psychiatric conditions.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways involving fluorinated ketones.
• Fine Chemical Production: Acts as a specialized building block for manufacturing high-value, complex organic compounds beyond pharmaceuticals.
• Process Chemistry & Optimization: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	2',5'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone
CAS No.	884504-26-1
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	2',5'-Difluoro-3-(1,3-dioxan-2-yl)propiophenone; 1-(2,5-Difluorophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3-(1,3-Dioxan-2-yl)-1-(2,5-difluorophenyl)propan-1-one; 2,5-Difluoro-β-oxo-benzenepropanal 1,3-dioxane acetal; Propiophenone, 2',5'-difluoro-3-(1,3-dioxan-2-yl)-; 884504-26-1; 2,5-Difluoro-3-(1,3-dioxan-2-yl)propiophenone
EINECS	Contact for details

Quality Control

Our 2',5'-Difluoro-3-(1,3-Dioxan-2-Yl)-Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.