Description

Ziprasidone Qt CAS NO 884305-07-1 is a high-purity pharmaceutical intermediate, specifically a key derivative in the synthesis of the atypical antipsychotic Ziprasidone. This compound is critical for ensuring the quality, efficacy, and consistency of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of neuropsychiatric therapeutics.

Application

• Primary Intermediate in the commercial synthesis of Ziprasidone Hydrochloride API.
• Process Development for optimizing manufacturing routes and scaling up production.
• Quality Control Reference Standard for analytical method development and validation.
• Research & Development of novel antipsychotic drug candidates and related benzisothiazolylpiperazine derivatives.
• Regulatory Filings, providing a critical starting material for Drug Master File (DMF) submissions.

Basic Information

Product Name	Ziprasidone Qt
CAS No.	884305-07-1
Molecular Formula	C21H21ClN4OS
Molecular Weight	412.94 g/mol
Synonyms	5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one; Ziprasidone Quinone Thioether; Ziprasidone QT Intermediate; 6-Chloro-5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-1,3-dihydro-2H-indol-2-one; Ziprasidone Key Intermediate; Benzisothiazolylpiperazine Ethyl Indolone Derivative
EINECS	Contact for details

Quality Control

Our Ziprasidone Qt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.