Description

2-Fluoro-4-Methoxyphenylacetic Acid is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a methoxy group and a fluorine atom on the phenylacetic acid scaffold, enabling precise modulation of electronic and steric properties in target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for high-performance display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials due to its tunable electronic properties.
• Complex Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs serving the global fine chemical market.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-Methoxyphenylacetic Acid
CAS No.	883531-28-0
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	(2-Fluoro-4-methoxyphenyl)acetic Acid; 2-Fluoro-4-methoxybenzeneacetic Acid; 4-Methoxy-2-fluorophenylacetic Acid; α-(2-Fluoro-4-methoxyphenyl)acetic Acid; 2-Fluoro-4-methoxy-α-toluic Acid; NSC 405124; FMPAA
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methoxyphenylacetic Acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.