Description

5-Bromo-2-Fluorophenylacetic Acid is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound is valued for its dual halogen functionality, which allows for selective cross-coupling reactions and further derivatization in complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of novel organic electronic materials and liquid crystals, where halogenated aromatic cores are critical.
• Custom Chemical Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers to produce bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-2-Fluorophenylacetic Acid
CAS No.	883514-21-4
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	(5-Bromo-2-fluorophenyl)acetic acid; 2-(5-Bromo-2-fluorophenyl)acetic acid; 5-Bromo-2-fluorobenzeneacetic acid; 883514-21-4; 5-Bromo-2-fluoro-α-toluic acid; 5-Bromo-2-fluorophenyl-acetic acid; 2-Fluoro-5-bromophenylacetic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorophenylacetic Acid is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.