Description

2-Chloro-4,5-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its versatile structure, which serves as a critical precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on new active ingredients, where the introduction of chlorine and fluorine atoms is key to modulating biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances lipophilicity and target binding.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance and stability in display technologies.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical companies for the custom production of complex, fluorinated compounds for client-specific projects.
• Academic & Industrial R&D: A valuable reagent in medicinal chemistry labs for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Product Name	2-Chloro-4,5-Difluorophenylacetic Acid
CAS No.	883502-00-9
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	(2-Chloro-4,5-difluorophenyl)acetic Acid; 2-Chloro-4,5-difluorobenzeneacetic Acid; α-(2-Chloro-4,5-difluorophenyl)acetic Acid; 883502-00-9; 2-Chloro-4,5-difluorophenyl-acetic acid; Acetic acid, 2-(2-chloro-4,5-difluorophenyl)-; 2-(2-Chloro-4,5-difluorophenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,5-Difluorophenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.