Description

Trifluoropyruvamide is a high-value fluorinated building block with the CAS registry number 883500-27-4. This compound is essential for introducing the trifluoromethylpyruvate moiety into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors and kinase-targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides and fungicides where the trifluoromethyl group enhances bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for fluorinated polymers and specialty chemicals with unique surface properties and resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and as a substrate for the preparation of complex fluorinated heterocycles and fine chemicals.
• Biochemical Tool Compound: Utilized in metabolic pathway studies and as a probe in enzymology research due to its structural mimicry.

Basic Information

Product Name	Trifluoropyruvamide
CAS No.	883500-27-4
Molecular Formula	C4H4F3NO2
Molecular Weight	155.08 g/mol
Synonyms	2-Oxo-3,3,3-trifluoropropanamide; 3,3,3-Trifluoropyruvamide; 3,3,3-Trifluoro-2-oxopropanamide; Trifluoropyruvic acid amide; α-Keto-β,β,β-trifluoropropionamide; TFPA; TFPAmide
EINECS	Contact for details

Quality Control

Our Trifluoropyruvamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and lot-to-lot consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.