Description

n-Methyl Iodofluoroacetamide is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique combination of reactive halogen and fluorine atoms, enabling precise molecular modifications that are difficult to achieve with other reagents. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and for use in radioiodination precursor work.

Application

• Pharmaceutical Intermediate: A key synthon for the incorporation of fluorine and iodine into potential drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, pesticides, and plant growth regulators that leverage fluorine's properties for enhanced efficacy and stability.
• Radioactive Tracer Development: Serves as a precursor molecule for the synthesis of compounds labeled with iodine-123 or iodine-125 for diagnostic imaging and research.
• Material Science: Employed in the development of specialty polymers and advanced materials where fluorinated segments impart unique surface properties or chemical resistance.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds in complex molecule assembly.
• Bioconjugation Chemistry: Useful for modifying peptides, proteins, or other biomolecules by reacting with nucleophilic amino acid side chains.

Basic Information

Product Name	n-Methyl Iodofluoroacetamide
CAS No.	883499-47-6
Molecular Formula	C3H5FINO
Molecular Weight	216.98 g/mol
Synonyms	N-Methyl-2-iodo-2-fluoroacetamide; 2-Fluoro-2-iodo-N-methylacetamide; Iodofluoro-N-methylacetamide; Acetamide, 2-fluoro-2-iodo-N-methyl-; Iodo(fluoro)acetic acid methylamide
EINECS	Contact for details

Quality Control

Our n-Methyl Iodofluoroacetamide is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, handling and storage should minimize exposure to direct light. Keep the container tightly sealed when not in use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.