Description

2-Bromo-3-Methoxy-1,1,1-Trifluoropropan is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and bromomethoxy functional groups, which are critical for modulating the physicochemical properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of advanced materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Advanced Material Building Block: Employed in the creation of specialty polymers and functional materials with tailored surface properties and chemical resistance.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and nucleophilic substitutions to introduce complex fluorinated fragments.
• Chemical Research & Development: A valuable tool for academic and industrial researchers exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	2-Bromo-3-Methoxy-1,1,1-Trifluoropropan
CAS No.	883498-92-8
Molecular Formula	C4H6BrF3O
Molecular Weight	207.00 g/mol
Synonyms	2-Bromo-3-methoxy-1,1,1-trifluoropropane; 1,1,1-Trifluoro-2-bromo-3-methoxypropane; 3-Methoxy-2-bromo-1,1,1-trifluoropropane; 2-Bromo-1,1,1-trifluoro-3-methoxypropane; 1-Bromo-2-methoxy-3,3,3-trifluoropropane; Propane, 2-bromo-3-methoxy-1,1,1-trifluoro-; (2-Bromo-3-methoxypropyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxy-1,1,1-Trifluoropropan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, keep the container tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.